Fig. 6.

Integrated biosensors for the real-time evaluation of wounds. (a) Scheme of zwitterionic PCB hydrogel dressing for the detection of pH value and glucose concentration in wound exudate. Reprinted with permission from Ref. [111]; Copyright 2020, John Wiley & Sons, Inc. (b) Overview illustration of smart dressing integrated with oxygen sensing and delivery patch. Reprinted with permission from Ref. [112]. (c) Schematic illustration of a stretchable and flexible smart bandage integrated with UA, pH, and temperature sensors, and a photograph of this device adhered on the hand for monitoring the condition and status of the wound. Reprinted with permission from Ref. [113]; Copyright 2020, Elsevier. (d) (ⅰ) A flexible multiplexed immunosensor integrated with a bio-inspired fluidic sampling system based on inter-connected half-open, sawtooth-shaped capillary channels with decreasing width, and a flexible wireless module for real-time monitoring of venous ulcers. (ii) Electromechanical sensing of cytokine and bacteria was based on aptamer modified graphene gold electrodes. Reprinted with permission from Ref. [18].