Table 2.
Characteristics of the NEO and the OBB cohort, as well as their combination
| Characteristics | NEOa | OBB | Totalb |
|---|---|---|---|
| Number of participants | 4,838 | 6,999 | 11,837 |
| Age (years) | 55.5 (6.0) | 41.6 (5.9) | 47.3 (5.9) |
| Men (%) | 42 | 44 | 43 |
| BMI (kg/m2) | 26.0 (4.3) | 25.8 (4.6) | 25.9 (4.5) |
| Fasting serum concentrations (mmol/L) | |||
| TG (median (IQR)) | 0.99 (0.71) | 0.93 (0.65) | 0.95 (0.67) |
| Total cholesterol | 5.80 (1.01) | 5.18 (1.01) | 5.43 (1.01) |
| LDL-cholesterol | 3.66 (0.94) | 3.22 (1.26) | 3.40 (1.13) |
| HDL-cholesterol | 1.60 (0.47) | 1.38 (0.42) | 1.47 (0.44) |
| APOA5 GRS (median (IQR)) | 0.86 (0.00) | 0.86 (0.00) | 0.86 (0.00) |
| LPL GRS (median (IQR)) | 0.48 (0.24) | 0.48 (0.24) | 0.48(0.24) |
Values are mean (SD), unless otherwise specified. GRS unit is in SD.
GRS, genetic risk score; IQR, interquartile range; NEO, Netherlands Epidemiology of Obesity; OBB, Oxford Biobank.
a
In NEO, the results are based on analyses weighted toward the reference BMI distribution of the general Dutch population.
b
The total represents averaged results from the individual analyses in NEO and OBB cohort.