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. 2022 Mar 28;28(6):862–872. doi: 10.1111/cns.13832

FIGURE 5.

FIGURE 5

Lithium improved outcomes after ICH through Gpr124‐mediated endothelial Wnt/β‐catenin signaling. (A) Hematoma volumes in mice with ICH. (B) Quantification of the hematoma volumes in mice. N = 4 mice per group. (C) Immunofluorescence staining of endogenous plasma IgG (green) leaking from vessels (red) after ICH in mice treated with or without LiCl. Scale bar, 100 μm. (D) Quantification of the relative IgG signal densities. n = 3 mice per group. *p < 0.05, **p < 0.01. ICH, intracerebral hemorrhage; BBB, blood–brain barrier