FIGURE 2.

Rb1 treatment improved lipid metabolism in HFD-fed rats. (A) Rats were provided with a high-fat diet for 2 weeks and then subjected to treatment with Rb1 (60 mg/kg) by gavage for 4 weeks. Blood samples of day 28 were used to test serum metabolic parameters, including (B) low-density lipoprotein cholesterol (LDL-c), (C) triglyceride (TG), (D) total cholesterol (TC), (E) high-density lipoprotein cholesterol (HDL-c), (F) glycosylated hemoglobin (GHb), and (G) blood glucose (Glu). (H) Body weight and (I) food intake were also recorded. (J) Oil red O (ORO) staining and hematoxylin and eosin (H&E) staining of liver tissues. (K) H&E staining of epididymal fat tissues. All data were expressed as the mean ± SEM (n = 8). Significant difference among groups were evaluated using one-way analysis of variance followed by Duncan’s post hoc test. *P < 0.05; **P < 0.01; ***P < 0.001. ns, not significant.