Table 3.

NODDI Imaging in White Matter Tracts.

Tract of Interest	P-value FDR corrected	P-value uncorrected	F	Partial Eta Squared
Isotropic Volume Fraction (Viso)
M1 TCATT	0.397	0.123	1.984	0.072
PMd TCATT	0.397	0.079	2.351	0.084
PMv TCATT	0.397	0.123	1.989	0.072
preSMA TCATT	0.397	0.185	1.649	0.060
SMA TCATT	0.397	0.088	2.261	0.081
S1 TCATT	0.439	0.303	1.233	0.046
M1 SMATT	0.439	0.310	1.214	0.045
PMd SMATT	0.540	0.422	0.948	0.036
PMv SMATT	0.397	0.210	1.542	0.057
preSMA SMATT	0.397	0.195	1.605	0.059
SMA SMATT	0.540	0.445	0.900	0.034
S1 SMATT	0.817	0.817	0.311	0.012
Nigrostriatal	0.817	0.775	0.370	0.014
Corticostriatal	0.400	0.235	1.449	0.053
STN to GP	0.397	0.188	1.635	0.060
MCP	0.561	0.495	0.805	0.030
SCP	0.397	0.028	3.203	0.111
Orientation Dispersion Index (ODI)
M1 TCATT	0.272	0.080	2.337	0.083
PMd TCATT	0.272	0.033	3.063	0.107
PMv TCATT	0.811	0.763	0.386	0.015
preSMA TCATT	0.272	0.073	2.411	0.086
SMA TCATT	0.051	0.003	5.135	0.167
S1 TCATT	0.287	0.152	1.810	0.066
M1 SMATT	0.276	0.130	1.941	0.070
PMd SMATT	0.276	0.123	1.987	0.072
PMv SMATT	0.545	0.449	0.892	0.034
preSMA SMATT	0.272	0.048	2.754	0.097
SMA SMATT	0.356	0.230	1.466	0.054
S1 SMATT	0.545	0.449	0.892	0.034
Nigrostriatal	0.276	0.106	2.107	0.076
Corticostriatal	0.545	0.399	0.997	0.037
STN to GP	0.756	0.667	0.524	0.020
MCP	0.923	0.923	0.160	0.006
SCP	0.311	0.183	1.658	0.061
Intracellular Volume Fraction (Vic)
M1 TCATT	0.868	0.842	0.277	0.011
PMd TCATT	0.868	0.524	0.753	0.029
PMv TCATT	0.868	0.349	1.114	0.042
preSMA TCATT	0.868	0.449	0.892	0.034
SMA TCATT	0.868	0.733	0.429	0.016
S1 TCATT	0.868	0.755	0.397	0.015
M1 SMATT	0.868	0.868	0.240	0.009
PMd SMATT	0.868	0.855	0.259	0.010
PMv SMATT	0.868	0.156	1.789	0.065
preSMA SMATT	0.868	0.744	0.413	0.016
SMA SMATT	0.868	0.685	0.498	0.019
S1 SMATT	0.868	0.576	0.665	0.025
Nigrostriatal	0.868	0.606	0.616	0.023
Corticostriatal	0.868	0.692	0.487	0.019
STN to GP	0.868	0.770	0.376	0.014
MCP	0.868	0.193	1.615	0.059
SCP	0.868	0.297	1.251	0.046

ANOVA results for main effect of group with age, sex, and site covariates.

Bold type indicates statistically significant values. Superscripts indicate significant post-hoc comparisons (P < 0.05, FDR-corrected).

TCATT: trans callosal tractography template, SMATT: sensorimotor area tract template, M1: Primary motor cortex, PMd: dorsal Premotor area, PMv: ventral Premotor area, SMA: supplementary motor area, S1: Primary sensory cortex, STN: subthalamic nucleus, GP: globus pallidus, MCP: middle cerebellar peduncle, SCP: superior cerebellar peduncle.

^aPD vs. Controls.

^bMSAp vs. Controls.

^cMSAp vs. PD.

^dPSP vs. Controls.

^ePSP vs. PD.

^fMSAp vs. PSP.