Table 4.
Free-Water Imaging in White Matter Tracts.
Tract of Interest | P-value FDR corrected | P-value uncorrected | F | Partial Eta Squared |
---|---|---|---|---|
Free-water (FW) | ||||
M1 TCATT | 0.121 | 0.089 | 2.253 | 0.080 |
PMd TCATT | 0.028b,c,d,e | 0.013 | 3.812 | 0.128 |
PMv TCATT | 0.116 | 0.073 | 2.411 | 0.085 |
preSMA TCATT | 0.028b.c.d | 0.011 | 3.937 | 0.132 |
SMA TCATT | 0.028b,c,d,e | 0.005 | 4.598 | 0.150 |
S1 TCATT | 0.116 | 0.075 | 2.393 | 0.084 |
M1 SMATT | 0.121 | 0.114 | 2.047 | 0.073 |
PMd SMATT | 0.028b,c | 0.011 | 3.942 | 0.132 |
PMv SMATT | 0.121 | 0.107 | 2.103 | 0.075 |
preSMA SMATT | 0.028b,d | 0.012 | 3.909 | 0.131 |
SMA SMATT | 0.028b,c,d,e | 0.002 | 5.235 | 0.168 |
S1 SMATT | 0.121 | 0.103 | 2.133 | 0.076 |
Nigrostriatal | 0.028d,e,f | 0.009 | 4.124 | 0.137 |
Corticostriatal | 0.116 | 0.075 | 2.388 | 0.084 |
STN to GP | 0.028d,e,f | 0.010 | 4.072 | 0.135 |
MCP | 0.121 | 0.099 | 2.165 | 0.077 |
SCP | 0.172 | 0.172 | 1.707 | 0.062 |
Free-water corrected Fractional Anisotropy (FAt) | ||||
M1 TCATT | 0.654 | 0.087 | 2.271 | 0.080 |
PMd TCATT | 0.654 | 0.172 | 1.711 | 0.062 |
PMv TCATT | 0.654 | 0.407 | 0.979 | 0.036 |
preSMA TCATT | 0.654 | 0.220 | 1.503 | 0.055 |
SMA TCATT | 0.654 | 0.028 | 3.198 | 0.110 |
S1 TCATT | 0.654 | 0.260 | 1.363 | 0.050 |
M1 SMATT | 0.654 | 0.477 | 0.838 | 0.031 |
PMd SMATT | 0.710 | 0.710 | 0.462 | 0.017 |
PMv SMATT | 0.654 | 0.443 | 0.904 | 0.034 |
preSMA SMATT | 0.654 | 0.579 | 0.660 | 0.025 |
SMA SMATT | 0.654 | 0.316 | 1.198 | 0.044 |
S1 SMATT | 0.654 | 0.315 | 1.200 | 0.044 |
Nigrostriatal | 0.654 | 0.036 | 3.001 | 0.103 |
Corticostriatal | 0.654 | 0.521 | 0.759 | 0.028 |
STN to GP | 0.654 | 0.072 | 2.421 | 0.085 |
MCP | 0.654 | 0.233 | 1.456 | 0.053 |
SCP | 0.654 | 0.125 | 1.974 | 0.071 |
ANOVA results for main effect of group with age, sex, and site covariates.
Bold type indicates statistically significant values. Superscripts indicate significant post-hoc comparisons (P < 0.05, FDR-corrected).
TCATT: trans callosal tractography template, SMATT: sensorimotor area tract template, M1: Primary motor cortex, PMd: dorsal Premotor area, PMv: ventral Premotor area, SMA: supplementary motor area, S1: Primary sensory cortex, STN: subthalamic nucleus, GP: globus pallidus, MCP: middle cerebellar peduncle, SCP: superior cerebellar peduncle.
aPD vs. Controls.
bMSAp vs. Controls.
cMSAp vs. PD.
dPSP vs. Controls.
ePSP vs. PD.
fMSAp vs. PSP.