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. 2022 Apr 28;80:104019. doi: 10.1016/j.ebiom.2022.104019

Figure 1.

Fig 1

ALKBH5 expression in osteosarcoma and its relationship to patient survival. a. High ALKBH5 tumor tissues exhibited lower total m6A methylation levels compared to low ALKBH5 group (t-test p = 0.0035, n = 41 per group). b. Representative images showing low or high expression of ALKBH5 by IHC staining. c. Kaplan-Meier survival analysis showed that the overall survival time of patients with low ALKBH5 expression was significantly shorter than that of patients with high ALKBH5 expression (log-rank p = 0.0283,n = 41 per group). d. Representative western blot showed the expression of ALKBH5 was markedly decreased in osteosarcoma (OS) compared with the normal bone (N). The data represent the mean± S.D. *P < 0.05 or **P < 0.01 indicates a significant difference between the indicated groups.