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. 2022 May 2;182(6):650ā€“659. doi: 10.1001/jamainternmed.2022.1449

Table 2. Differences in eGFRCysC Decline and Odds of Rapid Kidney Function Decline Over 2 Years in the Physical Activity and Exercise Arm vs the Health Education Arm (nā€‰=ā€‰1199).

Intervention effecta No. (95% CI) P value
Decline of eGFRCysC, mL/min/1.73 m2 0.96 (0.02-1.91)b .05
Odds of rapid decline 0.79 (0.65-0.97)c .03

Abbreviation: eGFRCysC, estimated glomerular filtration rate by cystatin C.

a

Adjusted for baseline eGFRCysC, sex, clinical sites, intervention, visit, and intervention-by-visit interaction.

b

Positive value indicates a lower rate of eGFRCysC decline.

c

Rapid decline defined by the high tertile threshold of 6.7%/y.