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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Chem Rev. 2021 Jun 15;121(13):7957–8094. doi: 10.1021/acs.chemrev.1c00138

Figure 15.

Figure 15.

Equilibrium between the ‘open’ (PDB 2FHX) and ‘closed’ (PDB 4BP0) conformations of SPM-1. Mobile regions are highlighted in blue (L3 loop), red (L10 loop) and green (α3 region). Reproduced with permission from reference348 Brem et al. Published by The Royal Society of Chemistry.