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Front and back view of IMP-1 showing the active-site loops (L10 and L3) and second-shell sphere regions involved in substrate recognition and turnover. Side chains of most relevant residues are shown as sticks, metal ligands as lines and Zn(II) ions as spheres (PDB 5EV6). L3 loop and Phe87 are shown in magenta, L10 in cyan.
