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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Chem Rev. 2021 Jun 15;121(13):7957–8094. doi: 10.1021/acs.chemrev.1c00138

Figure 2.

Figure 2.

Representation of the main mechanisms of β-lactam resistance in Gram-negative (left) and Gram-positive (right) bacteria. OM (outer membrane), PG (peptidoglycan), IM (inner membrane), CM (cytoplasmic membrane). The β-amino acid moiety resulting from β-lactam cleavage is shown in red.