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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Chem Rev. 2021 Jun 15;121(13):7957–8094. doi: 10.1021/acs.chemrev.1c00138

Figure 23.

Figure 23.

Phylogenetic tree of the VIM enzyme family. The 5 groups present within the family are highlighted in colors, and the locations of the reference enzymes within each group are shown in green. Protein sequences were aligned using Clustal Omega, phylogenetic trees were constructed using PhyML (via the phylogeny.fr web server) and tree representations were generated with iTOL.