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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Chem Rev. 2021 Jun 15;121(13):7957–8094. doi: 10.1021/acs.chemrev.1c00138

Figure 63.

Figure 63.

Structural model of the interaction of NDM-1 with the surface of lipid membranes (obtained from MD simulations by Prunotto et al.476). Active-site Zn(II) ions are shown as grey spheres. The N-terminal lipidated Cys and key residues for membrane interaction (Arg 39 and Arg46) are shown as spheres.