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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Chem Rev. 2021 Jun 15;121(13):7957–8094. doi: 10.1021/acs.chemrev.1c00138

Figure 69.

Figure 69.

Kinetic stability of MBLs in the bacterial periplasm depends on a balance between competing processes of MBL metallation (kon), de-metallation (koff), apo enzyme degradation (kdeg) and aggregation (kagg).