Table 2.
6-Month Hospitalization or Death Odds Ratios by Alcohol Use Category
| Unadjusted Model (n=9794) | Adjusted Model (n=9708) | |
|---|---|---|
| 6-month All-Cause Hospitalization or Death | Odds Ratio [95% confidence interval] | Odds Ratio [95% confidence interval] |
| Alcohol Use | ||
| AUDIT-C = Non-Drinker | 1.36 [1.19, 1.55] | 1.19 [1.03, 1.37] |
| AUDIT-C = Moderate Use | 1.00 (Ref) | 1.00 (Ref) |
| AUDIT-C = Hazardous Use | 1.15 [0.92, 1.44] | 1.15 [0.91, 1.47] |
| AUDIT-C = Harmful Use | 2.10 [1.55, 2.85] | 1.57 [1.12, 2.19] |
| AUD Diagnosis† (vs. no Diagnosis) | ─ | 1.07 [0.89, 1.28] |
| Age | ─ | Cubic Splineǂ |
| Male (vs. Female) | ─ | 1.18 [0.92, 1.51] |
| White (vs. Non-White) | ─ | 0.93 [0.83, 1.05] |
| Married (vs. Not Married) | ─ | 0.98 [0.87, 1.11] |
| Smoking Status | ||
| Never Smoker | ─ | 1.00 (Ref) |
| Former Smoker | ─ | 1.05 [0.89, 1.25] |
| Current Smoker | ─ | 1.35 [1.14, 1.60] |
| No Smoking Status | ─ | 1.17 [0.97, 1.40] |
| Unknown | ─ | 1.26 [1.02, 1.55] |
| JFI | ─ | 1.12 [1.08, 1.17] |
| Gagne (Without AUD Diagnosis) | ─ | 1.06 [1.03, 1.10] |
| 1-Year CAN Score | ─ | 1.07 [1.06, 1.08] |
| C Statistic = 0.54 | C Statistic = 0.70 | |
| Unadjusted Model (n=8521) | Adjusted Model (n=8440) | |
| 6-month CVD-related Hospitalization or Death | Odds Ratio [95% confidence interval] | Odds Ratio [95% confidence interval] |
| Alcohol Use | ||
| AUDIT-C= Non-Drinker | 1.50 [1.05, 2.15] | 1.25 [0.87, 1.80] |
| AUDIT-C= Moderate Use | 1.00 (Ref) | 1.00 (Ref) |
| AUDIT-C= Hazardous Use | 1.16 [0.63, 2.14] | 1.42 [0.76, 2.66] |
| AUDIT-C= Harmful Use | 0.83 [0.25, 2.70] | 1.10 [0.32, 3.81] |
| AUD Diagnosis (vs. no Diagnosis) | ─ | 0.61 [0.34, 1.10] |
| Age | ─ | Cubic Splineǂǂ |
| Male (vs. Female) | ─ | 3.40 [1.06, 10.87] |
| White (vs. Non-White) | ─ | 0.83 [0.62, 1.11] |
| Married or Cohabitating (vs. Not) | ─ | 0.91 [0.67, 1.24] |
| Smoking Status | ||
| Never Smoker | ─ | 1.00 (Ref) |
| Former Smoker | ─ | 1.44 [0.96, 2.17] |
| Current Smoker | ─ | 1.08 [0.68, 1.74] |
| No Smoking Status | ─ | 1.21 [0.75, 1.95] |
| Unknown | ─ | 1.45 [0.87, 2.42] |
| JFI | ─ | 1.07 [0.97, 1.18] |
| Gagne (Without AUD Diagnosis) | ─ | 1.12 [1.04, 1.20] |
| 1-Year CAN Score | 1.07 [1.04, 1.10] | |
| C Statistic = 0.55 | C Statistic = 0.74 | |
Notes. Adjusted model controls for age, race, gender, marital status, smoking status, JFI, Gagne, and 1-Year CAN. Age entered into model as cubic spline due to non-linear association with hospitalization or death logit. “Unknown” refers to patients with a smoking-related Health Factor where Current, Former, or Never Smoker status was unable to be coded. 95% Confidence Intervals in parentheses.
ǂ
Wald χ2=14.49, p<.01.
ǂǂ
Wald χ2=4.38, p=.22.
†
Interaction between AUD diagnosis and Audit-C category was not significantly associated with hospitalization or death; analyses were not stratified by AUD diagnosis.