Table II.

Prevalence of different pathological features in muscle biopsies according to the p62 status.

	p62 positive (n=132)	p62 negative (n=171)	univariate p-value	multivariate p-value	Total (n=303)
Inflammatory infiltrate	57% (75)	23% (39)	<0.001	0.002	38% (114)
Endomysial inflammation	41% (54)	9% (16)	<0.001	<0.001	23% (70)
Perimysial inflammation	14% (19)	10% (17)	0.2	0.8	12% (36)
Perivascular inflammation	31% (41)	17% (29)	0.004	0.04	23% (70)
Partial invasion of non-necrotic muscle fibres	27% (36)	5% (9)	<0.001	0.1	15% (45)
Degeneration	83% (110)	27% (46)	<0.001	<0.001	51% (156)
Regeneration	79% (104)	22% (38)	<0.001	<0.001	47% (142)
Perifascicular atrophy	11% (15)	7% (12)	0.2	0.7	9% (27)
COX negative	35% (46)	15% (26)	<0.001	0.1	24% (72)
Rimmed vacuoles	25% (33)	1% (2)	<0.001	0.003	12% (35)

Univariate analysis was performed using chi-square or Fisher’s exact test as appropriate.

Multivariate logistic regression analysis was adjusted for the type of disease.