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. 2022 Apr 11;35:10128. doi: 10.3389/ti.2022.10128

TABLE 2.

Characteristics of groups based on clustering.

Cluster/group
0 No response (n = 18) 1 Fast modulation (n = 15) 2 Slow modulation (n = 23) 3 Rise to sustained (n = 16) 4 Sustained (n = 16) All (n = 88)
Age (years, mean) 43.94 44.87 40.17 37.13 39.69 41.10
ESRF (years, mean) 13.08 7.33 10.65 12.16 14.23 11.48
Female (%) 55.56 93.33 78.26 31.25 43.75 61.36
LDKT (%) 94.44 100 95.65 93.75 75 92.05
Previous tx (%) 72.22 26.67 60.87 81.25 75 63.64
Crossmatch+ (%) 55.56 73.33 69.57 93.75 81.25 73.86
CDC+ (%) 11.11 13.33 17.39 37.5 25 20.45
Out of all CDC+, CDC>1:2 (%) 0 0 0 100 50 55.56
Pre Tx-DFPP(%) 66.7 80.0 82.6 93.7 62.5 77.27
Average tDSA value  2062 7023 7105 14813 12674 8735
DSA (n) 2 3 3 3 3 3
Rejection within first 30-days, % 16.67 80.0 56.52 56.25 18.75 47.73
Post Tx-DFPP (%) 5.56 33.33 13.04 18.75 6.25 14.77
Lymphocyte-depleting agent (%) 5.56 40 47.83 50 12.5 31.82
GF-5 years (%) 11.11 6.67 4.35 31.25 25 14.77

ESRF, end stage renal failure; LDKT, living donor kidney transplant; Tx, transplant; DFPP, double filtration plasmapheresis; CDC, Complement dependent cytoxicity.