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. 2013 Dec 13;2013(12):CD009448. doi: 10.1002/14651858.CD009448.pub2

Comparison 2. Unsupervised exercise training compared to no intervention.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 Annual rate of change in exercise capacity (ml/kg/min) (follow up > 6 months) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
2.2 Annual rate of decline FEV1 (% predicted) (follow up > 6 months) 1 65 Mean Difference (IV, Fixed, 95% CI) 2.01 [‐0.06, 4.08]
2.3 Change in FEV1 (% predicted) 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.3.1 At 3‐month follow up 1 35 Mean Difference (IV, Fixed, 95% CI) ‐0.75 [‐6.10, 4.60]
2.3.2 At 6‐month follow up 1 35 Mean Difference (IV, Fixed, 95% CI) 2.42 [‐5.42, 10.26]
2.3.3 At 12‐months follow up 1 31 Mean Difference (IV, Fixed, 95% CI) ‐0.36 [‐8.02, 7.30]
2.3.4 At 18‐months follow up 1 33 Mean Difference (IV, Fixed, 95% CI) 5.66 [‐2.88, 14.20]
2.3.5 At 24‐months follow up 1 28 Mean Difference (IV, Fixed, 95% CI) ‐1.72 [‐10.62, 7.18]
2.4 Annual rate of decline FVC (% predicted) (follow up > 6 months) 1 65 Mean Difference (IV, Fixed, 95% CI) 2.17 [0.47, 3.87]
2.5 Annual rate of decline FEF25-75 (% predicted) (follow up > 6 months) 1 65 Mean Difference (IV, Fixed, 95% CI) 0.80 [‐2.20, 3.80]
2.6 Change in lean body mass (kg) 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.6.1 At 3‐months follow up 1 35 Mean Difference (IV, Fixed, 95% CI) 1.76 [0.97, 2.55]
2.6.2 At 6‐months follow up 1 35 Mean Difference (IV, Fixed, 95% CI) 2.16 [0.55, 3.77]
2.6.3 At 12‐months follow up 1 30 Mean Difference (IV, Fixed, 95% CI) 1.88 [‐0.13, 3.89]
2.6.4 At 18‐months follow up 1 31 Mean Difference (IV, Fixed, 95% CI) 1.77 [‐0.80, 4.34]
2.6.5 At 24‐months follow up 1 28 Mean Difference (IV, Fixed, 95% CI) 1.82 [‐1.43, 5.07]
2.7 Change in skin fold measure (mm) 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.7.1 At 3‐months follow up 1 35 Mean Difference (IV, Fixed, 95% CI) ‐0.47 [‐4.42, 3.48]
2.7.2 At 6‐months follow up 1 35 Mean Difference (IV, Fixed, 95% CI) ‐2.54 [‐6.70, 1.62]
2.7.3 At 12‐months follow up 1 30 Mean Difference (IV, Fixed, 95% CI) ‐5.54 [‐10.86, ‐0.22]
2.7.4 At 18‐months follow up 1 31 Mean Difference (IV, Fixed, 95% CI) ‐5.03 [‐10.74, 0.68]
2.7.5 At 24‐months follow up 1 28 Mean Difference (IV, Fixed, 95% CI) ‐6.94 [‐14.02, 0.14]