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. Author manuscript; available in PMC: 2022 May 3.
Published in final edited form as: Stat Med. 2020 Sep 16;39(30):4651–4666. doi: 10.1002/sim.8746

FIGURE 2.

FIGURE 2

Boxplots of operating characteristics of a CRM design with 30 participants produced by the proposed method over 1000 different consistent vectors of true DLT probabilities using a skeleton o π = (0.03, 0.11, 0.25, 0.42, 0.58, 0.71). The upper plot presents the probability of correct selection (PCS) of the maximum tolerated dose (MTD); the middle plot presents average number of participants assigned to the MTD; the lower plot presents the average number of participants assigned to doses above the MTD. CRM, continual reassessment method