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. 2019 Apr 9;9(20):11054–11062. doi: 10.1039/c8ra05421e

Effect of spermine supplementation on the amino acids transporters mRNA levels in the liver of pigletsa.

Parameters Treatment time SEM p-Value
7 h 3 d 6 d 9 d
Con SP Con SP Con SP Con SP SP Time SP × time
SLC1A1 1.00a 1.68a 1.68a 2.93b 1.70a 3.90b 1.41a 11.37b 0.51 0.000 0.000 0.000
SLC1A5 1.00a 1.02a 1.93ab 2.83b 1.90ab 2.33ab 1.98ab 4.45b 0.18 0.000 0.000 0.034
SLC7A1 1.00a 1.14a 1.89ab 4.07b 1.81ab 5.51b 1.73ab 3.54b 0.24 0.000 0.000 0.000
SLC7A7 1.00 1.21 1.41 2.39 1.72 2.85 1.50 3.35 0.14 0.000 0.000 0.181
SLC7A9 1.00ab 1.07ab 0.78a 2.36cd 1.80c 4.04de 1.72bc 5.32e 0.22 0.000 0.000 0.000
SLC6A19 1.00 0.90 0.98 1.12 0.87 0.93 0.93 0.94 0.03 0.616 0.706 0.661
SLC15A1 1.00a 1.64ab 1.82b 2.30b 1.92b 5.69c 1.86b 3.60b 0.22 0.000 0.000 0.000
a

Con, control diet; SP, spermine-supplemented diet; SLC (7A1, 7A7, 7A9, 5A1, 6A19, 15A1), solute carrier family (7A1, 7A7, 7A9, 5A1, 6A19, 15A1). SEM, standard error of the mean (n = 6, number of replicates).a–e Mean in the same row with different superscripts are significantly different at P < 0.05.