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. 2022 Apr 19;12:810774. doi: 10.3389/fonc.2022.810774

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Copyright © 2022 Wu, Liu, Liu, Peng, Pang, Sun and Xia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Graphic abstract of current research hotspots of pancreatic cancer tumor microenvironment. (A) Mechanisms associated with a graphic abstract of the hypoxic microenvironment in PDAC. (B) The hotspots in clinical application of pancreatic cancer tumor microenvironment.