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. 2022 Apr 19;12:810774. doi: 10.3389/fonc.2022.810774

Table 4.

The 10 most cited articles regarding the tumor microenvironment of pancreatic cancer.

Title Corresponding authors Journal Publication Year Total Citations
Pancreatic cancer exosomes initiate premetastatic niche formation in the liver Stanger, BZ NATURE CELL BIOLOGY 2015 1013
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma Hingorani, SR CANCER CELL 2012 991
CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans Vonderheide, RH SCIENCE 2011 903
The Pancreas Cancer Microenvironment Tuveson, DA CLINICAL CANCER RESEARCH 2012 643
Gemcitabine Plus Bevacizumab Compared With Gemcitabine Plus Placebo in Patients With Advanced Pancreatic Cancer: Phase III Trial of the Cancer and Leukemia Group B (CALGB 80303) Kindler, HL JOURNAL OF CLINICAL ONCOLOGY 2010 577
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer Tuveson, DA GUT 2013 499
Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer Vonderheide, RH CANCER CELL 2012 485
CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models DeNardo, DG CANCER RESEARCH 2014 476
Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS(+)/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy Huber, PE CANCER CELL 2013 449
Stromal biology and therapy in pancreatic cancer Tuveson, DA GUT 2011 445