Table 3.

Cox proportional hazards model multivariable analysis for survival

Factor	Univariable HR (95% C.I)	p	Multivariable HR (95% C.I)	p
Blood NLR (< 4)	0.63 (0.47–0.84)	0.01	0.66 (0.45–0.96)	0.03
Pleural fluid lymphocyte predominance	0.52 (0.33–0.82)	0.01	0.53 (0.32–0.89)	0.02
Lymphocytic stroma predominance	0.74 (0.59–0.93)	0.01	0.55 (0.35–0.87)	0.01
Age (per year)	1.02 (1.01–1.04)	0.01	0.98 (0.95–1.01)	0.15
Male gender	0.85 (0.56–1.29)	0.45	0.66 (0.40–1.10)	0.11
WHO PS (3–4)	1.37 (1.12–1.67)	0.01	2.60 (1.72–3.92)	0.01
Epithelioid sub type	0.61 (0.44–0.846)	0.01	0.60 (0.39–0.93)	0.02
Radiological Stage (1 & 2 vs 3 & 4)	0.95 (0.53–1.69)	0.08	0.74 (0.32–1.69)	0.47
Received chemotherapy	0.52(0.40–0.70)	0.01	0.58 (0.40–0.84)	0.04

NLR neutrophil/lymphocyte ratio, p < 0.05 defined as significant