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. 2022 Apr 19;33(7-8):432–441. doi: 10.1089/hum.2021.287

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© Robert Klamroth et al. 2022; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Seropositivity for (A) the global population, (B) using the global HA weighted average, and by country for (C) AAV2, (D) AAV5, (E) AAV6, (F) AAV8, and (G) AAVrh10. Data are for adults and adolescents on day 1. Samples from Brazil were only tested using the AAV5 assay, not RUO assays. Global HA weighted average was calculated by multiplying the percentage of participants who tested positive in each country by the number of people with HA in that country, per 2018 WFH survey, divided by the total number of people with HA in all countries in this study, per 2018 WFH survey. AAV, adeno-associated virus; CI, confidence interval; HA, hemophilia A; RUO, research-use-only; WFH, World Federation of Hemophilia.