Table 1.
Demographic and biochemical parameters of MHD patients
| Item | Total | No Depressive Symptoms (n = 122) | Mild Depressive Symptoms (n = 26) | Moderate/Moderately Severe Depressive Symptoms (n = 12) | F/χ2 | P |
|---|---|---|---|---|---|---|
| Male, n (%) | 90 (56.2%) | 68 (55.7%) | 14 (53.9%) | 8 (66.7%) | 0.603 | 0.740 |
| Age (years) | 55.5 ± 13.1 | 55.12 ± 12.3 | 56.62 ± 14.12 | 56.67 ± 19.27 | 0.189 | 0.828 |
| Dialysis Duration (months) | 73.5 (29.3, 150.8) | 80 (30, 140) | 58 (33, 168) | 51 (19, 165) | 1.349 | 0.510 |
| SBP (mmHg) | 144.8 ± 21.3 | 145.2 ± 20.9 | 144.2 ± 22.4 | 140.8 ± 25.0 | 0.241 | 0.786 |
| DBP (mmHg) | 81.3 ± 12.7 | 81.1 ± 12.6 | 82.6 ± 14.0 | 80.4 ± 11.3 | 0.176 | 0.839 |
| Kt/V | 1.32 ± 0.15 | 1.32 ± 0.14 | 1.29 ± 0.13 | 1.36 ± 0.19 | 1.17 | 0.313 |
| Diabetic Mellitus (%) | 23 (14.38%) | 17 (13.93%) | 4 (15.38%) | 2 (16.5%) | 0.148 | 0.105 |
| Hypertension (%) | 24 (15.0%) | 18 (14.75%) | 4 (15.38%) | 2 (16.5%) | 0.138 | 0.995 |
| Transplantation, n (%) | ||||||
| Yes | 18 (11.3%) | 18 (14.75%) | 4 (15.38%) | 2 (16.5%) | 0.138 | 0.995 |
| No | 142 (88.7%) | |||||
| WBC (*109/L) | 5.99 ± 1.73 | 5.90 ± 1.67 | 6.58 ± 2.12 | 5.72 ± 1.13 | 1.841 | 0.162 |
| NEUT (*109/L) | 4.04 ± 1.37 | 3.93 ± 1.26 | 4.50 ± 1.88 | 4.08 ± 0.98 | 1.876 | 0.157 |
| LY (*109/L) | 1.23 ± 0.48 | 1.23 ± 0.48 | 1.26 ± 0.39 | 1.11 ± 0.63 | 0.435 | 0.648 |
| HGB (g/L) | 114.96 ± 13.63 | 115.70 ± 12.84b | 116.15 ± 16.29c | 104.75 ± 12.02 | 3.778 | 0.025* |
| RDW (%) | 14.14 ± 2.34 | 13.92 ± 1.77a | 15.16 ± 4.15 | 14.20 ± 1.60 | 3.096 | 0.048* |
| PLT(*109/L) | 184.32 ± 63.68 | 181.34 ± 59.70 | 201.04 ± 82.85 | 178.42 ± 54.89 | 1.083 | 0.341 |
| NLR | 3.74 ± 2.06 | 3.51 ± 1.42b | 3.85 ± 1.78c | 5.74 ± 5.17 | 6.947 | 0.001* |
| PLR | 153.77 (120.05–199.50) | 151.95 (122.64–191.21) | 169.47 (125.45–207.48) | 197.20 (103.64–232.38) | 1.374 | 0.503 |
| Alb(g/L) | 42.02 ± 3.24 | 42.29 ± 2.89b | 42.16 ± 3.03c | 39.06 ± 5.31 | 5.793 | 0.004* |
| BUN (mmol/L) | 22.8 ± 4.81 | 22.75 ± 4.48 | 23.07 ± 5.93 | 22.67 ± 5.76 | 0.051 | 0.951 |
| Scr (umol/L) | 859.91 ± 226.93 | 878.16 ± 213.29 | 834.16 ± 244.94 | 730.08 ± 289.72 | 2.576 | 0.079 |
| BUA (umol/L) | 431.19 ± 74.50 | 432.71 ± 71.68 | 444.88 ± 78.28 | 386.08 ± 84.12 | 2.722 | 0.069 |
| CHO (mmol/L) | 4.17 ± 1.04 | 4.22 ± 1.03 | 3.95 ± 1.16 | 4.10 ± 0.78 | 0.720 | 0.489 |
| TG (mmol/L) | 1.73 (1.15–2.65) | 1.81 (1.20–2.65) | 1.55 (1.15–2.82) | 1.64 (0.95–2.88) | 1.155 | 0.561 |
| Ferritin (ng/ml) | 160.5 (75.8–285.9) | 156.5 (75.0–286.1) | 189.9 (76.6–267.4) | 160.8 (66.6–300.0) | 0.205 | 0.903 |
| hsCRP (mg/L) | 3.67 (1.69–7.75) | 3.45 (1.67–7.15) | 3.67 (2.12–7.44) | 8.21 (0.58–13.15) | 0.947 | 0.623 |
| Charlson Comorbidity Index Score | 4.34 ± 1.75 | 4.28 ± 1.69 | 4.54 ± 1.68 | 4.58 ± 2.50 | 0.354 | 0.702 |
ap: no depressive symptoms group vs mild depressive symptoms group
b p: no depressive symptoms group vs moderate/moderately severe depressive symptoms group
cp: mild depressive symptoms group vs moderate/moderately severe depressive symptoms group
*Significant at p < 0.05
Values are means ± standard deviations or medians (25th–75th percentiles), unless otherwise specified
Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, WBC White blood cell, NEUT Neutrophil, LY lymphocyte, HGB Hemoglobin, RDW Red cell distribution width, PLT Platelet, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, Alb Albumin, BUN Blood urea nitrogen, Scr Serum creatinine, UA Uric acid, CHO Total cholesterol, TG Triglyceride, hsCRP High-sensitivity C-reactive protein