Table 6.
Experiment 2-diagnostic performance of the CNNs
| Test image set | Training image set | Sensitivity | Specificity | Accuracy | AUC | P-value for AUC† |
|---|---|---|---|---|---|---|
| Axial ADC map | Axial ADC map | 0.94 (0.87–0.98) | 0.87 (0.79–0.91) | 0.91 (0.83–0.95) | 0.95 (0.91–1.00) | – |
| All axial | 0.84 (0.76–0.90) | 0.87 (0.78–0.93) | 0.86 (0.77–0.91) | 0.93 (0.87–0.98) | 0.345 | |
| All | 0.90 (0.82–0.95) | 0.80 (0.72–0.86) | 0.86 (0.77–0.91) | 0.89 (0.81–0.96) | 0.069 | |
| Axial T2WI | Axial T2WI | 0.90 (0.83–0.95) | 0.83 (0.74–0.88) | 0.87 (0.79–0.92) | 0.90 (0.84–0.96) | – |
| All T2WI | 0.92 (0.85–0.96) | 0.89 (0.81–0.94) | 0.91 (0.83–0.95) | 0.94† (0.88–0.99) | 0.218 | |
| All axial | 0.86 (0.79–0.91) | 0.87 (0.78–0.93) | 0.87 (0.78–0.92) | 0.90 (0.84–0.97) | 0.934 | |
| All | 0.90 (0.83–0.95) | 0.85 (0.76–0.90) | 0.88 (0.80–0.93) | 0.91† (0.85–0.98) | 0.627 | |
| Sagittal T2WI | Sagittal T2WI | 0.90 (0.82–0.95) | 0.80 (0.72–0.86) | 0.86 (0.77–0.91) | 0.88 (0.81–0.95) | – |
| All T2WI | 0.94 (0.87–0.98) | 0.80 (0.72–0.85) | 0.88 (0.80–0.92) | 0.92† (0.86–0.98) | 0.188 | |
| All sagittal | 0.90 (0.83–0.95) | 0.83 (0.74–0.88) | 0.87 (0.79–0.92) | 0.91† (0.84–0.97) | 0.507 | |
| All | 0.86 (0.79–0.91) | 0.87 (0.78–0.93) | 0.87 (0.78–0.92) | 0.92† (0.85–0.98) | 0.424 | |
| Axial CE-T1WI | Axial CE-T1WI | 0.84 (0.71–0.93) | 0.89 (0.76–0.96) | 0.87 (0.78–0.93) | 0.93 (0.87–0.98) | – |
| All CE-T1WI | 0.84 (0.77–0.89) | 0.91 (0.83–0.96) | 0.88 (0.80–0.92) | 0.93 (0.89–0.98) | 0.716 | |
| All axial | 0.92 (0.85–0.97) | 0.78 (0.70–0.83) | 0.86 (0.78–0.90) | 0.88 (0.80–0.95) | 0.086 | |
| All | 0.86 (0.78–0.92) | 0.84 (0.76–0.91) | 0.86 (0.77–0.91) | 0.91 (0.85–0.97) | 0.589 | |
| Sagittal CE-T1WI | Sagittal CE-T1WI | 0.90 (0.83–0.95) | 0.83 (0.74–0.88) | 0.87 (0.79–0.92) | 0.90 (0.84–0.97) | – |
| All CE-T1WI | 0.86 (0.79–0.91) | 0.87 (0.78–0.93) | 0.87 (0.78–0.92) | 0.92† (0.87–0.98) | 0.524 | |
| All sagittal | 0.90 (0.83–0.95) | 0.85 (0.76–0.90) | 0.88 (0.80–0.93) | 0.91† (0.85–0.98) | 0.696 | |
| All | 0.98 (0.92–1.00) | 0.83 (0.76–0.84) | 0.91 (0.84–0.92) | 0.95† (0.89–1.00) | 0.156 |
Diagnostic performance of the CNNs in the testing using single image sets with the addition of other image sets for training
ADC, Apparent Diffusion Coefficient; T2WI, T2 weighted image; CE-T1WI, contrast-enhanced T1 weighted image
† vs. the CNN trained with the single image set