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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Jul 29;228:108923. doi: 10.1016/j.drugalcdep.2021.108923

Table 3.

Assessment of risk of bias for non-randomized studies.

# Author, date Was there a
comparison?
How were the individuals/groups
assigned?
Was the baseline
allocation to
intervention
prospective?
Was outcome
assessment
prospective?
Was hypothesis
generation
prospective?
Study
quality
rating
1-9★
Psychosocial Interventions
9 Bloom-Foster and Mehl-Madrona (2020) No All patients initiating outpatient OUD treatment with buprenorphine Yes Yes Probably Yes n/a
10 Brown et al. (2014) No Patients recruited from the community Yes No Information No Information n/a
11 Montoya et al. (2005) No Secondary analysis RCT No Probably No Probably No n/a
12 Moore et al. (2012) Yes By therapist availability Yes Yes Yes 7 stars
13 Moore et al. (2016) Yes Secondary analysis, RCT No Probably Yes Probably No 5 stars
14 Weiss et al. (2014) Yes Secondary analysis, RCT No Probably Yes Probably No 6 stars
Technological Interventions
17 Schuman-Olivier et al. (2018) No “Unstable young adults struggling in OBOT” were referred by buprenorphine prescribers. Yes Yes Yes n/a
Complementary & Integrative Treatments
19 Lander et al. (2018) Yes Volunteers stable on buprenorphine for 90+days, control group matched on key attributes (age, sex, days abstinent) Yes Yes Probably Yes 5 stars
Structural Barriers to Care
20 Cochran et al. (2018) No Treatment-seeking volunteers Yes Probably Yes Probably Yes n/a

Risk of bias (ROB) for studies with a comparison was evaluated using the Newcastle-Ottawa ROB assessment tool. Nine stars represents the lowest risk of bias, 1 star the highest risk of bias. Studies without a comparison arm were not scored using the tool and are listed as n/a in the final column.