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. 2019 Apr 15;9(21):11718–11721. doi: 10.1039/c9ra01692a

Association constant Ka valuesa of the chiral acceptor and 3-BARF pairs.

Entry XB acceptor K a, M−1
1 (R)-8 6.1 ± 0.7
2 (S)-8 6.0 ± 0.8
3 (R)-9 94 ± 7
4 (S)-9 91 ± 5
a

Association constant Ka measured in CDCl3 at 298 K and determined by fitting the 1H NMR titration data to 1 : 1 binding isotherm of BindFit.15 The given Ka and standard error are the calculated mean values of two parallel experiments. Full details given in the ESI.