TABLE 4.

Kinetic parameters of the interaction of Streptomyces sp. strain K15 and R61 dd-peptidases with Lek 156 and Lek 157

Compound	Streptomyces sp. strain K15 dd-peptidase				Streptomyces sp. strain R61 dd-peptidase
	k2/K′ (M−1 s−1)	K′ (M)	k2 (s−1)	k3 (s−1)	k2/K′ (M−1 s−1)	K′ (M)	k2 (s−1)	k3 (s−1)
Lek 156	0.57 ± 0.01	>5 × 10−3	>3 × 10−3	≤5 × 10−5	9 ± 0.6	>3.5 × 10−4	>4 × 10−3	(3 ± 0.5) × 10−5
Lek 157	6.8 ± 0.2	>5 × 10−4	>4 × 10−3	(4 ± 2) × 10−5	45 ± 1	>1.5 × 10−4	>7 × 10−3	(2.2 ± 0.2) × 10−5