Table 2.

List of eRNAs involved in inflammatory immune diseases.

Disease	Affected cell	Enhancer or SE	eRNA	Regulated gene	Mechanism	Function	Reference
Gastritis	Gastric adenocarcinoma cells	IL1 enhancer	IL1 eRNA	IL1	Mediation of NF-kB	Influence inflammatory gene expression	(92)
	Gastric epithelial cells	BIRC3 enhancer	BIRC3 eRNA	BIRC3 cIAP2	Induction of caspase-3 activation	Improve apoptosis resistance in gastric epithelial cells	(94)
Inflammatory bowel disease	CD14+ cells	IFNG	IFNG-R-49	IL22 IL26	No	Regulate inflammatory factors	(138)
Systemic Lupus Erythematosus	Monocyte	Enhancer 2	eRNA157	ADAMDEC1	Mediation of MAP kinase and p300-NFκB	Regulate of SLE-related inflammatory gene expression	(93)
Autoimmune uveitis	CD4+ T cells	SEs	Ifng eRNA	Th1 gene	Recruition of media and P-TEFb	Promote cell-specific gene expression	(91)
Recurrent pregnancy loss	Trophoblast cells	No	lnc-SLC4A1-1	CXCL8	Recruition of NFκB and CXCL8	Exacerbate inflammatory response	(95)
Hypoxia	Cardiomyocytes	No	HERNA1	SMG1 SYT17	Mediation of phosphatidylinositol 3-kinase-related kinases	Regulate of hypoxic progression and metabolism	(141)