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Fig. 5. Light microscopy of testes tissue in different groups. H&E ×200: (A–D, Control group, HFD group, HFD + GSPE (100 mg kg−1) group and HFD + GSPE (300 mg kg−1) group). (A) In control group, normal testicular architecture was seen; (B) after HFD treatment, severe testes damage was noted; (C and D) there was an improvement in the seminiferous tubule structure in GSPE-treated HFD rats.