TABLE 3.

Regional measures showing significant differences among participants in the T2DM-MCI, T2DM-N, and HCs groups.

		Post hoc tests
Measurements	p(F)	T2DM-MCI vs. HCs	T2DM-MCI vs. T2DM-N	T2DM-N vs. HCs
Nodal degree
Hippocampus_L	0.003	0.002	0.050	0.519
Superior frontal gyrus, orbital part _R	0.003	0.007	0.009	0.996
Hippocampus_R	0.003	0.002	0.252	0.132
Inferior temporal gyrus _L	0.007	0.007	0.061	0.696
Superior occipital gyrus _R	0.008	0.019	0.020	1.000
Inferior frontal gyrus, orbital part_L	0.010	0.011	0.060	0.785
Parahippocampal gyrus_L	0.010	0.009	0.097	0.616
Anterior cingulate gyrus _R	0.012	0.024	0.030	0.996
Superior frontal gyrus, orbital part _L	0.015	0.039	0.026	0.986
Supplementary motor area _L	0.024	0.065	0.033	0.960
Caudate nucleus _R	0.045	0.035	0.366	0.470
Middle temporal gyrus _R	0.046	0.044	0.177	0.797
Paracentral lobule _L	0.046	0.035	0.401	0.438
Nodal efficiency
Hippocampus_L	0.002	0.002	0.055	0.434
Superior frontal gyrus, orbital part _R	0.003	0.005	0.012	0.962
Hippocampus_R	0.004	0.002	0.193	0.201
Anterior cingulate gyrus _R	0.005	0.010	0.019	0.971
Inferior temporal gyrus _L	0.006	0.006	0.041	0.762
Inferior frontal gyrus, orbital part_L	0.008	0.008	0.063	0.078
Superior frontal gyrus, orbital part _L	0.009	0.029	0.015	0.967
Superior occipital gyrus _R	0.012	0.023	0.032	0.991
Paracentral lobule_R	0.037	0.026	0.420	0.355
Temporal Pole, middle temporal gyrus_L	0.045	0.039	0.237	0.994
Olfactory cortex _L	0.046	0.051	0.136	0.897

Comparisons of regional measures among participants in the three groups (p < 0.05, false-positive rate corrected, shown in bold) and post hoc pairwise comparisons (p < 0.05, shown in bold) were performed using Tukey’s t-test. Please refer to Supplementary Figure 1 for more details. T2DM-MCI, type 2 diabetes mellitus patients with mild cognitive impairment; T2DM-N, type 2 diabetes mellitus patients without mild cognitive impairment; HCs, healthy controls; L, left; R, right.