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. 2022 Apr 4;22(9):1650–1679. doi: 10.1039/d1lc01168e

Fluid pumping capabilities of artificial cilia reported in the literature. In the table, these artificial cilia are arranged according to their length from small to large. The best ones in terms of generated absolute maximum flow speed and normalized flow speed are marked in bold and italic, respectively. (μ) MAC = (microscopic) magnetic artificial cilia.

Cilia type Fabrication method Cilia geometry Actuation method Cilia motion Working fluid Maximum flow speed Beating frequency Local Remax Normalized flow speed Fluid pumping mechanism
l × w × t [μm3] v [m s−1] f [Hz] ρvl δ = v/fl
l × d [μm2]
μMAC12b Self-assembly 20 × 3 Uniform rotating magnetic field 3D tilted conical motion Water 3 5 0.01 0.030 3D non-reciprocal motion
μMAC8a Tracked-etched polycarbonate membranes as templates 25 × 0.7 Uniform rotating magnetic field 3D tilted conical motion Water 8 34 ≦0.025 0.009 3D non-reciprocal motion
μMAC10a Self-assembly 31 × 4.4 Uniform rotating magnetic field 3D tilted conical motion Water 5 0.5 <1 0.0323 3D non-reciprocal motion
μMAC102a Photolithography techniques 70 × 20 × 0.4 Uniform rotating magnetic field 2D non-reciprocal motion Water 50 <1 2D non-reciprocal motion
μMAC11a Photolithography techniques 70 × 20 × 0.4 Non-uniform rotating magnetic field 2D non-reciprocal motion Water 130 10 <1 0.186 2D non-reciprocal motion
Electrostatic cilia6a Micro-systems technology processing 100 × 20 × 1 AC voltage 2D non-reciprocal motion Silicone oil 600 200 1 0.030 Inertia
μMAC104b Two-mask lithographic process 200 × 20 × 0.07 Nearly uniform rotating magnetic field 2D non-reciprocal motion Water 1350 62 0.09–0.6 0.109 2D non-reciprocal motion
μMAC14b Continuous roll-pulling method Conical shape 250 Uniform rotating magnetic field 3D tilted conical motion Water 120 20 6 0.024 3D non-reciprocal motion
μMAC13b Magnetic fiber drawing (self-assembly) 300 Uniform rotating magnetic field 3D tilted conical motion Water 70 50 0.005 3D non-reciprocal motion
μMAC9b Photolithography techniques 300 × 100 × 15 Uniform rotating magnetic field 2.5D non-reciprocal motion Water 500 50 <1 0.033 2.5D non-reciprocal motion
μMAC15b Micro-molding 350 × 50 Uniform rotating magnetic field 3D tilted conical motion Water 260 40 15 0.018 3D non-reciprocal motion
2D metachronal μMAC138b Micro-molding 350 × 50 Non-uniform periodical magnetic field 2D non-reciprocal motion Water 3000 100 920 0.086 2D non-reciprocal motion + inertia + metachrony
2D metachronal μMAC20b Micro-molding 350 × 50 Uniform rotating magnetic field 2D symmetric motion Water 220 10 50–700 0.063 Inertia + metachrony
2D metachronal MAC85a Hand-assembly 1000 × 550 × 100 Uniform rotating magnetic field 2D non-reciprocal motion Glycerol 450 2.5 <0.1 0.180 2D non-reciprocal motion + metachrony
3D metachronal MAC19a Molding 4000 × 800 Uniform rotating magnetic field 3D non-reciprocal motion Glycerol 83 0.083 <1 0.250 3D non-reciprocal motion + metachrony
2D metachronal pneumatic metachronal cilia89a Moulding 8000 × 1000 Pneumatically 2D non-reciprocal motion Water 19 000 30 3480 0.079 2D non-reciprocal motion + inertia + metachrony
2D metachronal pneumatic metachronal cilia91a Moulding 14 000 × 1000 Pneumatic-hydraulic pressure 2D non-reciprocal motion Glycerol 500 0.25 0.04 0.143 2D non-reciprocal motion + metachrony
a

Maximum local flow above the cilia tips.

b

Maximum global flow in the channel. Note that the normalized flow speed is calculated regardless the chip geometry and the amount of cilia.