| Number | Percentage of women that would change breast cancer risk classification after addition of PRS-313 to BOADICEA IKNL guideline | ||||
|---|---|---|---|---|---|
| IKNL guideline | NICE guideline | NCCN guideline | |||
| All cases | 3,925 | 34 | 36 | 27 | |
| All controls | 3,479 | 5 | 11 | 5 | |
| Cases with gene panel result | Non-carriers | 2,313 | 34 | 34 | 27 |
| ATM carriers | 40 | 23 | 23 | 0 | |
| CHEK2 carriers | 164 | 27 | 24 | 7 | |
| PALB2 carriers | 10 | 0 | 0 | 0 | |
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