| Table 1. Final candidate genes to gastric cancer predisposition. | |
|---|---|
| Function | Genes |
| Germline cancer predisposition | APC, ATM, SDHC, COL7A1, GPC3, RNF43, EXT2, POLD1, EXT1, POT1, PTCH1, POLH, GATA2, BAP1, ERCC2 and FANCA |
| Cell adhesion | FAT1, FAT2, FAT4 and CTNND1 |
| Tumor suppression genes | PHF2, LARP7, LRP1B, WWOX, ADAMTS9, LATS1, BCL6B, ITIH5, NEO1, MAD1L1, GPX7, IQGAP2, DACT2, SIRT3, RCC1 and EPHB2 |
| Helicobacter pylori recognition | IL12A, TLR1, TLR2, TLR5, TLR10, A4GNT and MUC1 |
| DNA repair | UNG, KAT5, RAD23A, HBP1 and LIG3 |
| Other related functions | ARID4A, ARID1B, ATP4A and ROBO1 |
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