Comparison of frequencies of MB-COMT, DRD2 and NR3C1 methylation between SCZ patients with control | ||||||
---|---|---|---|---|---|---|
Methylation | Genotype | Schizophrenia | Healthy Control | OR | 95% Cl | p* |
n = 110 (%) | n = 100 (%) | |||||
COMT | Unmethylation | 68 (61.8) | 43 (43.0) | 0.466 | 0.268-0.809 | .006* |
Partial Methylation | 42 (38.2) | 57 (57.0) | 0.466 | 0.268-0.809 | ||
DRD2 | Unmethylation | 0 (0.0) | 14 (14) | 0.439 | 0.375-0.514 | .000* |
Partial Methylation | 110 (100.0) | 86 (86) | 0.439 | 0.375-0.514 | ||
NR3C1 | Unmethylation | 107 (97.3) | 9 (9) | 0.003 | 0.001-0.011 | .000* |
Partial Methylation | 3 (2.7) | 91 (91) | 0.003 | 0.001-0.011 | ||
Abbreviations | *, Pearson chi-square | OR, odds ratio | CI, confidence interval |