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. 2022 Apr 7;30(Suppl 1):88–608. doi: 10.1038/s41431-021-01026-1
Comparison of frequencies of MB-COMT, DRD2 and NR3C1 methylation between SCZ patients with control
Methylation Genotype Schizophrenia Healthy Control OR 95% Cl p*
n = 110 (%) n = 100 (%)
COMT Unmethylation 68 (61.8) 43 (43.0) 0.466 0.268-0.809 .006*
Partial Methylation 42 (38.2) 57 (57.0) 0.466 0.268-0.809
DRD2 Unmethylation 0 (0.0) 14 (14) 0.439 0.375-0.514 .000*
Partial Methylation 110 (100.0) 86 (86) 0.439 0.375-0.514
NR3C1 Unmethylation 107 (97.3) 9 (9) 0.003 0.001-0.011 .000*
Partial Methylation 3 (2.7) 91 (91) 0.003 0.001-0.011
Abbreviations *, Pearson chi-square OR, odds ratio CI, confidence interval