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. 2022 Apr 8;78(Pt 5):571–585. doi: 10.1107/S2059798322002261

Figure 9.

Figure 9

(a) Fluorescence-based competition assay. Various coumarin core-containing inhibitors were pre-incubated with Hsp90αMC before adding MDCC, the fluorescence intensity of which was monitored over time. Models of derrubone (b) and chlorobiocin (c) bound in Hsp90αMC (chain A, green; chain B, cyan; chain C, magenta).