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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Nat Protoc. 2022 Feb 4;17(3):567–595. doi: 10.1038/s41596-021-00649-4

Table 7 |.

ENIGMA ACRI Checklist, short form

Categories Subcategories Main items

Participant Inclusion/Exclusion Criteria Inclusion and exclusion criteria for all participant groups
Characteristics Basic Demographics Age and sex/gender for all participant groups
Advanced Demographics I Education or a measurement of intelligence for all participant groups
Advanced Demographics II Race or ethnicity for all participant groups
Psychiatric Profile Any categorical or dimensional measurement of psychopathologies other than substance use disorder
Handedness Handedness for all participant groups
Substance Use Profile-Main Drug Route(s) of administration for the main substance (if it is obvious (i.e., there is only one route of administration for cigarette smokers or alcohol drinkers), then it does not need to be reported,)
Substance Use Profile-Main Drug Current and lifetime use pattern/severity for the main drug of use for all participant groups
Substance Use Profile-Other Drugs Measures of current or lifetime use pattern/severity for drugs, other than the main drug of use, for all participant groups
Abstinence Status Days/hours/minutes since last use (duration of abstinence) and how abstinence was verified for all participant groups
Addiction Treatment Status Treatment status for all participant groups (e.g., non-treatment-seeking active users, treatment-seeking active users, undergoing active treatment, treated and abstinent, relapsed after treatment)
General fMRI Information fMRI Pulse Sequence and Other Acquisition Details fMRI data acquisition details
fMRI Preprocessing Pipeline and Other Details fMRI preprocessing details
fMRI Data Processing fMRI analyses and statistical modeling details
fMRI Data Reporting Basic whole-brain response to drug cues
General Task Task Design Task structure (event, block or mixed (events in blocks))
Information Number of Task Components Number of runs (if more than one), blocks (for block-designed studies) and events (e.g., drug cues, control cues, fixations)
Requested Engagement Instructions to the study participants on how to engage with the cues
Temporal Information of the Event/Block Duration Duration of each cue (for both event and blocked-design tasks) and the total block duration (for blocked-design tasks)
Temporal Information of the Task Total task duration
Order of Blocks/Events Order of block types (e.g., drug and control) (for blocked-designs) or event types (e.g., drug and control) (for event-related designs)
(The order can be fully randomized (randomized and different between subjects), pseudorandomized (identical between subjects but randomized once for the order of events/blocks) or not randomized (fixed order like neutral-drug-neutral-drug for all subjects)
Data and Resource-Sharing Sharing the behavioral task code or source images
Cue Information Sensory Modality of Cues Modality(ies) of the utilized drug and neutral/control cues (The modalities can be word, picture, smell, taste, tactile, audio script, written script, imagination, silent video, audiovisual video, paraphernalia, substance itself or mixed.)
Sources of Cues, Development Source of drug and neutral/control cues
Sources of Cues, Validation Extent of prior validation of drug and neutral/control cues used in the study (Drug and neutral/control cues in a study might be not validated or validated by assessing the craving induction of each cue individually using simple-item craving instruments like a single-item VAS or using standardized instruments of craving assessment and emotion or stress reactivity)
Drug and Neutral/Control Cue Content Content of drug cues and its relationship to the targeted drug (These include stimulus related to the drug, stimulus related to instruments of drug use, stimulus related to various stages of drug use (e.g., ‘beginning’ or ‘end’ stimuli (lit cigarette vs. ashtray)), stimulus related to drug intake, stimulus related to typical drug consumption environments, stimulus related to preparation of drug, stimulus related to purchasing the drug)
Neutral/Control Matching to Drug Cues for Physical Features Factors for which drug and neutral/control cues have been matched (e.g., color, brightness, hue, content, complexity, scrambled drug cue)
Craving Assessment Inside Scanner Craving Assessment Inside Scanner, Presence Craving assessment inside the scanner
Craving Assessment Inside Scanner, Time Points Description of the time points at which craving-related assessment is performed inside the scanner (e.g., before and/or after each cue/event/ block/trial/scan/run/session) (Yes/No/Not Applicable (in cases when there is no assessment inside the scanner))
Craving Assessment Inside Scanner, Instrument(s) Description of the instrument(s) used to assess craving and craving- related constructs inside the scanner (Yes/No/Not Applicable (in cases when there is no assessment inside the scanner))
Craving Assessment Inside Scanner, Technology Description of the hardware used to obtain participant responses, with specifications of models and brands of devices if necessary (e.g., response box and fiber-optic pad) (Yes/No/Not Applicable (in cases when there is no assessment inside the scanner))
Craving Assessment Outside Scanner Craving Assessment Outside Scanner, Presence Any craving-related assessment outside the scanner
Craving Assessment Outside Scanner, Time Points Description of the time points at which craving-related assessment is performed outside the scanner (e.g., immediately before entering the scanner or immediately after exiting the scanner) (Yes/No/Not Applicable (in cases when there is no assessment outside the scanner))
Craving Assessment Outside Scanner, Instrument(s) Description of the instrument(s) used to assess craving and craving- related constructs outside the scanner (Yes/No/Not Applicable (in cases when there is no assessment outside the scanner))
Pre- and Post-Scanning Considerations Pre-Scanning Training and Familiarization Procedure to train/familiarize participants with the task/scanner before the scanning
Pre-Scanning Drug and Smoking Consumption Whether participants were allowed to smoke or use other drugs before scanning
Other Tasks and Procedures in the Imaging Session Presence and order of other tasks and procedures (e.g., resting fMRI or DTI before drug-cue reactivity or familiarization) in the imaging session
Post-Scanning Craving Management Steps taken to reduce participant craving after performing the task

This form contains only the main items and excludes the additional recommendations.