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. 2022 Apr 19;13:882198. doi: 10.3389/fphar.2022.882198

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Copyright © 2022 Liu, Zhao, Zhu, Wang, Liu, Nie, Zhao, Wang and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of rhynchophylline on cardiac appearance and morphology. (A) Representative heart photographs of each group. (B) The left ventricular weight index (LVWI) and cardiac weight index (CWI). (C) Representative sections (magnification, ×400) of cardiac tissue morphology stained by hematoxylin and eosin in each group. (D) Pathology scores; (E) Representative sections (magnification, ×400) of cardiac tissue morphology stained by Masson’s trichrome stain in each group; (F) Positive area rate of MASSON staining. Values are presented as mean ± standard error of the mean. **p < 0.01 vs. control group; #p < 0.05 vs. type 2 diabetes mellitus group.