Table 1.
Baseline cohort characteristics
| Characteristic | Kingston Cohort | CanPREDDICT | ||
|---|---|---|---|---|
| CHIP (n=18) | No CHIP (n=69) | CHIP (n=25) | No CHIP (n=60) | |
| Age | 70.9±11.8 | 62.0±13.4 | 75.7±4.6 | 73.1±5.7 |
| Female | 9 (50) | 29 (42) | 9 (36) | 18 (30) |
| Baseline eGFR (CKD-EPI) | 23.4±11.6 | 28.4±11.3 | 26.1±9.3 | 28.9±8.7 |
| UACR (mg/g) | 248 [36, 1126] | 149 [30, 770] | 96 [24, 245] | 161 [26, 331] |
| Microalbuminuria (UACR≥30 mg/g) | 14 (78) | 48 (75) | 16 (64) | 42 (70) |
| Macroalbuminuria (UACR≥300 mg/g) | 8 (44) | 26 (41) | 6 (24) | 17 (28) |
| Hypertension, N (%) | 18 (100) | 63 (91) | 25 (100) | 60 (100) |
| Diabetes, N (%) | 6 (33) | 27 (39) | 15 (60) | 34 (57) |
| Smoking, N (%) | 8 (44) | 40 (58) | Unavailable | |
| Dyslipidemia, N (%) | 14 (78) | 61 (88) | 19 (76) | 52 (87) |
| Cause of CKD | 6 DKD 5 HTN 7 unknown/other | 24 DKD 20 HTN 25 unknown/other | 10 DKD 11 HTN 4 unknown/other | 28 DKD 24 HTN 8 unknown/other |
Data are presented as mean±SD, median [interquartile range], or count (percentage). CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; DKD, diabetic kidney disease; HTN, hypertension.