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. 2022 May;33(5):1033–1044. doi: 10.1681/ASN.2021111488

Table 2.

Pathologic findings in FAT1-associated MN

Patient Number Number of Glomeruli Number of Sclerosed Glomeruli Interstitial Fibrosis and Tubular Atrophy (%) IF Microscopy TBM Deposits EM Stage
1 17 2 20 IgG 3+, C3 1+, IgG4 3+ No I
2 17 6 20 IgG 3+, C3 1+ Yes II
3 43 18 60 IgG 3+, C3 1+, IgG4 3+ Yes II
4 86 68 80 IgG 3+, C3 1+ Yes II
5 36 4 20 IgG 3+ No II
6 6 1 20 IgG 3+, C3 1+ No II
7 57 2 5 IgG 3+, C3 1+, IgG4 3+, IgG2 2+ No II
8 50 9 5 IgG 2+, C3 1+ No II
9 55 2 10 IgG 2+, IgG4 2+ No II
10 41 2 10 IgG 3+, C3 1+, IgG4 3+ No II
11 18 1 10 IgG 2+, C3 1+, IgG4 3+ No II
12 16 0 10 IgG 2+ No I
13 7 0 20 IgG 1–2+, C3 1+ No I
14 16 4 20 IgG 3+, C3 1+ No I

Mayo Clinic cohort patients 1–5 and 11–14; Cedars Sinai cohort patients 6–10. EM, electron microscopy.