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. 2022 Apr 19;9:870370. doi: 10.3389/fnut.2022.870370

Table 2.

Highlighted IPA canonical pathways.

Ingenuity canonical pathways –log (p-value) Gene symbol
Kinetochore metaphase signaling pathway 1.61E+01 AURKB,BUB1B,CDCA8,CDK1,CENPK,CENPL,CENPO,H2AC18/H2AC19,KIF2C,KNL1, KNTC1,MASTL,NUF2,PMF1/PMF1-BGLAP,PPP1R14A,SKA1,SPC25, STAG3,TTK,ZWINT
Cell cycle control of chromosomal replication 4.89E+00 CDC45,CDC6,CDK1,MCM2,MCM5,ORC1,TOP2A
Role of BRCA1 in DNA damage response 3.04E+00 BLM,BRCA2,BRIP1,E2F7,FAAP24,RFC4
Tumor microenvironment pathway 3.00E+00 CCL2,COL1A1,COL1A2,COL3A1,CSPG4,FGF14,MMP1, MMP17,MMP28
NER (Nucleotide Excision Repair, Enhanced Pathway) 1.82E+00 CHAF1B,GTF2H4,POLD3,RFC4,TOP2A
Mismatch repair in eukaryotes 1.68E+00 EXO1,RFC4
Cyclins and cell cycle regulation 1.51E+00 CDK1,E2F7,HDAC10,SUV39H1
Role of CHK proteins in cell cycle checkpoint control 1.34E+00 CDK1,E2F7,RFC4