Substrate scope screening of sulfonate saltsa.
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General conditions: 1n–1r (2.0 mmol), 2 (2.2 mmol), TBAB (32.2 mg, 5 mol%), CH3CN (10 mL, 0.2 M); KHF2 (468 mg, 3.0 eq.), acetone (10 mL, 0.2 M); 1s–1u (0.2 mmol), 2 (0.44 mmol), TBAB (6.4 mg, 10 mol%), CH3CN (1 mL, 0.2 M); KHF2 (93.6 mg, 6.0 eq.), acetone (1 mL, 0.2 M). In the bracket shows the corresponding product and its isolated yield.
Yields were determined by HPLC using 4-methylbenzenesulfonyl fluoride (3a) as the external standard.