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. 2022 May 3;17(5):e0267729. doi: 10.1371/journal.pone.0267729

Table 1. Participant characteristics.

Characteristic Control (n = 310) Case (n = 155)
Age (mean, SD) 31.9 (7.8) 30.6 (7.8)
Gender
    Male 264 (85.2%) 142 (91.6%)
    Female 46 (14.8%) 13 (8.4%)
Country
    Australia 4 (1.3%) 2 (1.3%)
    Brazil 12 (3.9%) 6 (3.9%)
    Canada 14 (4.5%) 7 (4.5%)
    Dominican Republic 2 (0.6%) 1 (0.6%)
    Haiti 4 (1.3%) 2 (1.3%)
    Peru 68 (21.9%) 34 (21.9%)
    USA 206 (66.5%) 103 (66.5%)
Race and Ethnicity *
    White 152 (49.0%) 79 (51.0%)
    Black 43 (13.9%) 15 (9.7%)
    Multiracial or Other Race 12 (3.9%) 11 (7.1%)
    Mestizo/a 68 (21.9%) 34 (21.9%)
    Hispanic 35 (11.3%) 16 (10.3%)
Vaccine trial treatment arm
    Intervention 177 (57.1%) 86 (55.5%)
    Comparison 133 (42.9%) 69 (44.5%)
AD5 Titer stratum
    >18 176 (56.8%) 84 (54.2%)
    < = 18 134 (43.2%) 71 (45.8%)
Behavioral Risk score (mean, SD) ** 2.8 (1.2) 3.3 (1.2)
Circumcised (male participants) 157 (59.5%) 84 (59.2%)
HSV-2 seropositive (male participants) 81 (30.7%) 57 (40.1%)

*Race and ethnicity were asked in a singular question about self-identity in the parent study without option of multiselect; options including race or ethnicity therefore sum to 100%.

**Combined risk score for male and female includes theoretical and observed range 0–7 points.