Table 2. LTBI status, Mtb-specific CD4 T-cell activation, and HIV acquisition.
CoR Score | Univariate regression estimates | Multivariate regression estimates | ||
---|---|---|---|---|
ORa (95% CI) | p-value | aORa,b (95% CI) | p-value | |
LTBI Positivec | 0.84 (0.51, 1.39) | 0.51 | 0.85 (0.51, 1.43) | 0.54 |
PFSd | 0.96 (0.78, 1.18) | 0.68 | 0.96 (0.77, 1.20) | 0.73 |
FSd | 0.94 (0.76, 1.16) | 0.57 | 0.95 (0.76, 1.18) | 0.62 |
Unadjusted and adjusted odds ratios for LTBI status, COMPASS polyfunctional scores (PFS) and functional scores (FS) in those who acquired HIV versus controls.
aAll models used conditional logistic regression accounting for matching variables (treatment arm and country).
bModels were fully fit with all variables that were associated with case control status: gender, risk score, and age.
cPrespecified as the primary exposure of interested.
dORs are reported for 1 standard deviation change.