Table 3.
Allele and genotype frequencies in patients and controls.
| SNP ID | Allele/genotype frequency n (%) | P value (OR) | ||||||
|---|---|---|---|---|---|---|---|---|
| Control (%) | AITD (%) | GD (%) | HT (%) | AITDs vs. C | GD vs. C | HT vs. C | ||
| rs6568431 | A | 461 (30.17) | 563 (34.16) | 375 (33.91) | 188 (34.69) | 0.016 (1.201) | 0.042(1.187) | 0.052 (1.229) |
| C | 1067 (69.83) | 1085 (65.84) | 731 (66.09) | 354 (65.31) | ||||
| AA | 67 (8.76) | 88 (10.68) | 59 (10.57) | 29 (10.70) | 0.044 | 0.114 | 0.124 | |
| AC | 327 (42.80) | 387 (46.97) | 257 (46.47) | 130 (47.97) | ||||
| CC | 370 (48.44) | 349 (42.35) | 237 (42.76) | 112 (41.33) | ||||
|
| ||||||||
| rs548234 | C | 382 (25.00) | 455 (27.61) | 307 (27.76) | 148 (27.31) | 0.095 (1.144) | 0.112 (1.153) | 0.052 (1.229) |
| T | 1146 (75.00) | 1193 (72.39) | 799 (72.24) | 394 (72.69) | ||||
| CC | 53 (6.94) | 64 (7.77) | 43 (7.78) | 21 (7.75) | 0.213 | 0.242 | 0.124 | |
| CT | 276 (36.13) | 327 (39.68) | 221 (39.96) | 106 (39.11) | ||||
| TT | 435 (56.93) | 433 (52.55) | 289 (52.26) | 144 (53.14) | ||||
|
| ||||||||
| rs6937876 | G | 444 (29.05) | 550 (33.37) | 374 (33.82) | 176 (32.47) | 0.009 (1.223) | 0.009 (1.247) | 0.136 (1.174) |
| A | 1084 (70.95) | 1098 (66.63) | 732 (66.18) | 366 (67.53) | ||||
| GG | 70 (9.16) | 89 (10.80) | 61 (11.03) | 28 (10.33) | 0.020 | 0.023 | 0.277 | |
| AG | 304 (39.80) | 372 (45.15) | 252 (45.57) | 120 (44.28) | ||||
| AA | 390 (51.04) | 363 (44.05) | 240 (43.40) | 123 (45.39) | ||||