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. 2022 Apr 26;2022:6560154. doi: 10.1155/2022/6560154

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Copyright © 2022 Qing Wu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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RAPGEF2 knockdown promotes tumor growth in HCC cancer xenografts. (a) Western blotting examination of MHCC97 cells transfected with either control (Ctrl) or RAPGEF2 shRNA. (b, c) The tumor growth curve and weights of the tumors were determined. (d, e) Fluorescence-activated cell sorting (FACS) study of CD56+CD3-natural killer cells in MHCC97 xenograft tumors with either control (Ctrl) or RAPGEF2 shRNA. Data represents the mean ± SD, n = 10 per group. ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001.