Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mean concentrations of linezolid in plasma for peak and trough samples
| Linezolid dose (mg/kg) (no. of animals) | Mean day 1 concn (μg/ml) in plasma ± SD at:
|
Mean day 5 concn (μg/ml) in plasma ± SD at:
|
||
|---|---|---|---|---|
| 1 h (peak) | 8 h (trough) | 1 h (peak) | 8 h (trough) | |
| 25 (4) | 4.7 ± 4.0 | 0.28 ± 0.42 | 9.0 ± 3.9 | 0.09 ± 0.07 |
| 50 (12) | 11.7 ± 10.9 | 0.23 ± 0.52 | 25.8 ± 11.5 | 4.13 ± 5.95 |
| 75 (13) | 18.5 ± 15.0 | 0.23 ± 0.26 | 54.8 ± 23.2 | 10.8 ± 5.0 |
