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. 2021 Apr 24;91(4):937–946. doi: 10.1038/s41390-021-01528-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a A heatmap demonstrating levels of the 20 proteins most significantly correlating to gestational age (GA) and/or retinopathy of prematurity (ROP). Visits and clustering from ROP stage are also shown. b Longitudinal results for the proteins matrix extracellular phosphoglycoprotein (MEPE), paired immunoglobulin-like type 2 receptor beta (PILRB), and angiopoietin-1 (ANGPT1) show distinctions in protein levels between the infants with different stages of ROP. MEPE and PILRB are both correlated to both GA and ROP and ANGPT1 correlated to ROP. The longitudinal results of all the 20 most correlating proteins are shown in Supplementary Figure S1 (online).