Table 1.
MIC that null mutants of genes identified as being statistically significant loci by treeWAS stop growing at, against the A1160 control
| A1160 gene ID | Af293 gene ID | MIC (mg l−1) | treeWAS P | Gene description | Locus |
|---|---|---|---|---|---|
| AFUB_063960 | AFUA_4G06890 | >0.0625 | <2.03 × 10−6 | cyp51A | L98H |
| AFUB_016810 | AFUA_1G17440 | >0.25 | 0.001546976 | abcA | Y1149N |
| AFUB_014520 | AFUA_1G14960 | >1 | 0.001546976 | Has domain(s) with predicted actin binding activity | A820V |
| AFUB_014700 | AFUA_1G15150 | >1 | 0.003190639 | Orthologue(s) have hydrolase activity | L100F |
| AFUB_014780 | AFUA_1G15230 | >1 | 0.004462783 | Orthologue(s) have role in conidiophore development | Synonymous SNP |
| AFUB_014950 | AFUA_1G15410 | >1 | 0.000502209 | Has domain(s) with predicted zinc ion binding activity | S109P |
| AFUB_015010 | AFUA_1G15460 | >1 | 0.000200224 | Orthologue of Aspergillus nidulans FGSC A4: AN0892 | Synonymous SNP |
| AFUB_015020 | AFUA_1G15470 | >1 | 0.005395385 | Orthologue(s) have RNA polymerase II transcription factor activity | Synonymous SNP |
| AFUB_015060 | AFUA_1G15520 | >1 | 0.001956814 | Orthologue(s) have allophanate hydrolase activity | F2S |
| AFUB_015190 | AFUA_1G15660 | >1 | 0.005395385 | Orthologue of NRRL 181: NFIA_009670 | L71S |
| AFUB_015200 | AFUA_1G15670 | >1 | 0.001956814 | Putative laccase | Synonymous SNP |
| AFUB_016310 | AFUA_1G16920 | >1 | 0.005567187 | Beta-xylosidase | Synonymous SNP |
| AFUB_016610 | AFUA_1G17220 | >1 | 0.0000936 | Putative secreted polygalacturonase GH-28 | Intron |
| AFUB_016620 | AFUA_1G17230 | >1 | 0.000359083 | Orthologue(s) have carbon-oxygen lyase activity | P466T |
| AFUB_016750 | AFUA_1G17380 | >1 | 0.000200224 | Has domain(s) with predicted oxidoreductase activity | I68V |
| AFUB_016800 | AFUA_1G17430 | >1 | 0.00000228 | Orthologue(s) have monophenol monooxygenase activity | E586D |
| AFUB_016830 | AFUA_1G17470 | >1 | 0.00000305 | nrtB | Intron |
| AFUB_016850 | AFUA_1G17490 | >1 | 0.001152366 | Has domain(s) with predicted carbohydrate binding | G298S |
| AFUB_017000 | AFUA_1G17620 | >1 | 0.000887684 | Orthologue of RIB40: AO90011000197 | Synonymous SNP |
| AFUB_032840 | AFUA_2G17190 | >1 | 0.005886174 | Has domain(s) with predicted ATP binding | P1013A |
| AFUB_045240 | AFUA_3G03010 | >1 | 0.000887684 | Putative phosphate-repressible phosphate permease | Synonymous SNP |
| AFUB_057290 | AFUA_5G09740 | >1 | 0.004617329 | Orthologue(s) have role in conidiophore development | E432K |
| AFUB_084890 | AFUA_8G01700 | >1 | 0.003128212 | Has domain(s) with predicted catalytic activity | Synonymous SNP |
| AFUB_085680 | AFUA_8G00900 | >1 | 0.002175055 | Orthologue of FGSC A4: AN8368 | T47M |
| AFUB_085750 | AFUA_8G00820 | >1 | 0.000397402 | Orthologue of RIB40: AO90138000119 | H16R |
| AFUB_085820 | AFUA_8G00750 | >1 | 0.0000406 | Has domain(s) with predicted DNA binding | Synonymous SNP |
| AFUB_086150 | AFUA_8G00420 | >1 | 0.001260979 | C6 finger transcription factor fumR | N305D |